Oncogene - Coordinate regulation of estrogen receptor β degradation by Mdm2 and CREB-binding protein in response to growth signals Skip to main content Thank you for visiting nature.com.

The estrogen receptors (ERs) belong to a group of ligand-inducible transcription factors known as the nuclear receptor superfamily (Laudet et al., 1992).Members of the family share several ...

Association Between Estrogen Receptor-β Expression and Epidermal Growth Factor Receptor Mutation in the Postoperative Prognosis of Adenocarcinoma of the Lung. JCO 27 , 411-417 (2009). DOI: 10.1200/JCO ...

Adenocarcinoma of the lung unrelated to a smoking habit occurs more frequently in women than men, thus suggesting an association between female hormones and development of these tumors. The aim of ...

Estrogen acts on bone cells, which contain both isoforms of estrogen receptors. 21,22 However, concentrations of estrogen receptor β are higher in developing cancellous bone, whereas ...

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...

AUGUSTA, Ga. – A receptor mutation that essentially blocks estrogen's action has been identified for the first time in a female, researchers report. The 18-year-old wasn't experiencing breast ...

Estrogen receptor expression may help explain why more males have autism Date: September 9, 2014 Source: Medical College of Georgia at Georgia Regents University ...

Mutations in the androgen-receptor gene have been shown to cause androgen resistance in 46,XY humans 1,2 and in murine models, 3 but estrogen-receptor mutations are rare. The action of estrogen in ...

Scientists know that estrogen can protect the brain, but the details are hazy. Two new papers, each focusing on a different estrogen receptor, now bring the picture into sharper focus. In the May 13 ...

An estrogen receptor that promotes cancer also causes drug resistance. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2021 / 09 / 210923122418.htm ...