Moreover, recent studies have shown that the aberrant activation of the EMT and Wnt/β-catenin pathway also contributes to enzalutamide resistance ... that could be construed as a potential conflict of ...

Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.

Our study also uncovers a novel coordinated function of TGF-β and GRO chemokines responsible for guiding neutrophil trafficking to the breast tumor. In the present study, we compared the neutrophil ...

SRC1 was the first cloned steroid receptor co-activator that interacts with steroid hormone receptors to promote transcriptional activation in a hormone-dependent manner. The p160 SRC family ...

Correspondence to Dr Jörg Distler, Department of Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Ulmenweg 18, Erlangen D-91054, Germany; ...

These studies suggest that dexamethasone and cAMP might act synergistically or cooperatively to stimulate the expression of the ANG gene in the liver. β-Adrenergic receptors are present in mouse liver ...

Prior to menopause, natural estrogen production helps decrease the risk of a heart attack. After menopause, though, estrogen levels fall, and by age 60 to 65, men and women have approximately the same ...

1Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

This important study shows that the activity of hypothalamic hypocretin/orexin neurons (HONs) correlates with body movement over multiple behaviors. Sophisticated techniques and analyses showcase this ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...