The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estrogen response element in the 5' untranslated region. J Neurochem 2013; 127: 487–495.

Association Between Estrogen Receptor-β Expression and Epidermal Growth Factor Receptor Mutation in the Postoperative Prognosis of Adenocarcinoma of the Lung. JCO 27 , 411-417 (2009). DOI: 10.1200/JCO ...

Estrogen acts on bone cells, which contain both isoforms of estrogen receptors. 21,22 However, concentrations of estrogen receptor β are higher in developing cancellous bone, whereas ...

Scientists know that estrogen can protect the brain, but the details are hazy. Two new papers, each focusing on a different estrogen receptor, now bring the picture into sharper focus. In the May 13 ...

AUGUSTA, Ga. – A receptor mutation that essentially blocks estrogen's action has been identified for the first time in a female, researchers report. The 18-year-old wasn't experiencing breast ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...

Mutations in the androgen-receptor gene have been shown to cause androgen resistance in 46,XY humans 1,2 and in murine models, 3 but estrogen-receptor mutations are rare. The action of estrogen in ...

Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University ...

Risk Factors. Endogenous Hormones: High lifetime exposure to estrogen and progesterone increases the risk of hormone receptor positive breast cancer. Exogenous Hormones: A study by Salagame et al ...