The physiological effects of estrogens are mediated by two intracellular transcription factors, the estrogen receptors (ERs), that regulate transcription of target genes through binding to specific ...

The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in breast cancers has been intensely studied; however, there is still no real consensus regarding the clinical utility of an ...

Sex differences in brain and behavior are ubiquitous in sexually reproducing species. One cause of sexual dimorphisms is developmental differences in circulating concentrations of gonadal steroids.

Cadenza Bio, Inc. today announced that a collaborative study, "Chloroindazole based Estrogen Receptor β ligands with ...

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

FLD is a metabolic dysfunction encompassing several liver pathologies, ranging from intracellular triglycerides accumulation to severe lipotoxicity and fibrosing steatohepatitis, all of which are ...

Announcing a new publication for Acta Materia Medica journal. Endocrine therapy that blocks estrogen receptor signaling has been effective for decades as a primary treatment choice for breast cancer ...

BioWorld - Thursday, June 19, 2025 Breaking News: Trump administration impacts continue to roil the life sciences sector See today's BioWorld Science Home » A carborane agonist of estrogen receptor β ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...

Adenocarcinoma of the lung unrelated to a smoking habit occurs more frequently in women than men, thus suggesting an association between female hormones and development of these tumors. The aim of ...