The estrogen receptors (ERs) belong to a group of ligand-inducible transcription factors known as the nuclear receptor superfamily (Laudet et al., 1992). Members of the family share several ...

Published: 25 March 2014 Estrogen receptor β and Liver X receptor β: biology and therapeutic potential in CNS diseases M Warner & J-A Gustafsson Molecular Psychiatry 20, 18–22 (2015) Cite this ...

The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in breast cancers has been intensely studied; however, there is still no real consensus regarding the clinical utility of an ...

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

Association Between Estrogen Receptor-β Expression and Epidermal Growth Factor Receptor Mutation in the Postoperative Prognosis of Adenocarcinoma of the Lung. If you have the appropriate software ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...

First, target cells for estrogen action contain varying concentrations of homodimers of one or both of two species of estrogen receptors — estrogen receptor α and estrogen receptor β — as ...

A receptor mutation that essentially blocks estrogen's action has been identified for the first time in a female, researchers report.

Although androgen resistance has been characterized in men with a normal chromosome complement and mutations in the androgen-receptor gene, a mutation in the gene encoding estrogen receptor α ...

Estrogen receptor expression may help explain why more males have autism Date: September 9, 2014 Source: Medical College of Georgia at Georgia Regents University Summary: The same sex hormone that ...

Scientists know that estrogen can protect the brain, but the details are hazy. Two new papers, each focusing on a different estrogen receptor, now bring the picture into sharper focus. In the May 13 ...

An estrogen receptor that promotes cancer also causes drug resistance Date: September 23, 2021 Source: University of California - San Francisco Summary: Cancer cells proliferate despite a myriad ...