The estrogen receptors (ERs) belong to a group of ligand-inducible transcription factors known as the nuclear receptor superfamily (Laudet et al., 1992).Members of the family share several ...

The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in breast cancers has been intensely studied; however, there is still no real consensus regarding the clinical utility of an ...

Adenocarcinoma of the lung unrelated to a smoking habit occurs more frequently in women than men, thus suggesting an association between female hormones and development of these tumors. The aim of ...

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

(Funded by Pfizer and Arvinas Estrogen Receptor; VERITAC-2 ClinicalTrials.gov number, NCT05654623.) Notes. This article was published on May 31, 2025, at NEJM.org.

Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University ...

New generation estrogen receptor-targeted agents in breast cancer: present situation and future prospectives. Acta Materia Medica. 2024. Vol. 3(1):57-71. DOI: 10.15212/AMM-2024-0006. DOI.

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed ...

How estrogen's millisecond-fast action happens Date: October 2, 2024 Source: Baylor College of Medicine Summary: Researchers discovered a mechanism by which estrogen can trigger fast neuronal ...

CYP46A1-overexpressing females had as much estrogen in their brains as did wild-type females but expressed 25 percent more estrogen receptor β in their hippocampi. ERβ protein levels also increased by ...

Researchers at Huntsman Cancer Institute identified potential new treatment options for people with endometrial cancer.Endometrial cancer is the most common gynecological cancer and high levels of ...