Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the ...

Upon binding to estrogen, both the membrane estrogen receptors, α and β, activate ERK–related kinases, leading to cell proliferation 1. Estrogen is known to activate the ERK signaling pathway ...

Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.

Current models of resistance discovered in genomic studies of breast cancer tumors which are understudy include: Rho GDIa, the androgen receptor (AR), Dicer1, breast cancer resistance protein (BCRP1), ...