Why does the rooster crow and the hen does not? This question prompted the scientist Arnold Adolph Berthold to castrate a ...

HER2 tumor marker tests are used to determine whether breast cancer is HER2 positive or negative. A person is a candidate for ...

Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University ...

Vepdegestrant is an oral proteolysis-targeting chimera (PROTAC) estrogen receptor (ER) degrader that directly harnesses the ubiquitin–proteasome system.In this phase 3, open-label, randomized ...

Risk Factors. Endogenous Hormones: High lifetime exposure to estrogen and progesterone increases the risk of hormone receptor positive breast cancer. Exogenous Hormones: A study by Salagame et al ...

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed ...

Estrogen is also theorized, says Javaid, to contribute to the onset of mild cognitive decline commonly associated (affecting up to 62% of women) with perimenopause and menopause, like brain fog ...

Panelists discuss the EMBER-3 trial, which evaluated single-agent oral selective estrogen receptor degrader (SERD) ...

Researchers at Huntsman Cancer Institute identified potential new treatment options for people with endometrial cancer.Endometrial cancer is the most common gynecological cancer and high levels of ...

Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor–Positive Human Epidermal Growth Factor 2–Negative Breast Cancer. ... these results will make treatment decisions more complex for ...

The researchers propose that interacting with the ER-alpha-Clic1 complex enables estrogen to trigger fast neuronal responses through Clic1 ion currents. The study appeared in Science Advances .