Thyroid hormones (T) and estrogens (E) are nuclear receptor ligands with at least two molecular mechanisms of action: (i) relatively slow genomic effects, such as the regulation of transcription by ...

Estrogen's direct genomic effects are mediated by the nuclear form of the estrogen receptors ERα or ERβ which associate with the Estrogen Response Element (ERE) or the fos/jun heterodimers that bind ...

This is a preview. Log in through your library . Abstract Nuclear receptors can activate diverse biological pathways within a target cell in response to their cognate ligands, but how this ...