Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

Collagens and elastin in the extracellular matrix, which forms a scaffold to support organs, cause the immune system's natural killer cells to switch off their 'killer' function. The hypertension drug ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...