This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

All analyte injections were performed at a flow rate of 30 μL/min for 120 s and a dissociation time of 360 s (600 s was used in the assay of ... 150 mM tris (2-carboxyethyl) phosphine, and 0.8% formic ...