Healio6h
Q&A: ‘An exciting breakthrough’: Gene transfer therapy promising in Danon disease
Danon disease is a rare but serious cardiomyopathy that drastically reduces life expectancy. Male patients infrequently live ...
eLife20h
Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
Hosted on MSN1mon
Researchers uncover principles of gene expression regulation in cancer and cellular functions
A research team at KAIST has identified the core gene expression networks regulated ... altering the three-dimensional structure of the SRF protein. This interaction facilitates the ...
Gene Hackman died a week after the rare hantavirus killed his wife, officials say
Betsy Arakawa, 65, died from hantavirus pulmonary syndrome, and the Oscar-winning actor, who was in poor health with advanced ...
Medical Xpress2y
News on gene therapy
Researchers from the NIHR Moorfields Biomedical Research Centre and University College London have found that gene therapy improved visual acuity and preserved retinal structure in young children ...
Phys.org28d
Gene editing approach sheds light on how mitochondria drive autophagy
One innovative aspect of this study is the methodology used: the team employed CRISPR-Cas9 gene editing to label the MFN1 and MFN2 proteins within the cell, without resorting to artificial ...