Most species of bacteria can be broadly divided into two groups, known as gram-positive and gram-negative. These categories ...

Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope biology, defining the primary function of an important protein complex ...

Gram-positive and gram-negative bacteria differ in the composition of their cell walls. Gram-negative bacteria have a double layer of protection, making them more difficult to kill, Muñoz said.

Zosurabalpin is able to destroy Gram-negative bacteria by jamming LPS molecules inside the bacteria, weakening its membrane. It is the first of its class of antibiotics, and the first new class of ...

In fact, the authors noted, Gram-negative bacteria represent four of the top six pathogens causing antibiotic-associated deaths, with some studies indicating that 75% of deaths from drug-resistant ...

A new drug candidate able to fight off 300-plus types of drug-resistant bacteria in the laboratory may be used one day to treat stubborn infections in humans, researchers said Wednesday.

Gram-negative bacteria are notoriously difficult to drug because of their tough outer membranes. Existing antibiotics have a hard time getting through, ...

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem ...