N-亚硝胺类化合物是国际癌症研究机构认定的2A类致癌物 [1]。这类物质能够直接损伤细胞DNA，诱发基因突变，进而促进肿瘤形成。由于其较强的毒性，ICH M7将之列为“关注阵列”物质 [2]。在人用药品中，处方、工艺、包材、生产和贮藏环境等因素均可能导致N-亚硝胺类杂质的产生， 原料药 中出现N-亚硝胺类化合物与 原料药 自身制备过程，以及 溶剂 ...

MS usually shows up in people between the ages of 20 and 40. Common early signs of MS are vision problems, numbness, and tingling. There is no cure for MS, but some treatments can help slow it down.

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Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...

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Elevating your legs can help reduce swollen feet by moving excess fluid back toward your heart. Wearing elastic stockings can help reduce swelling and should be put on in the morning before your legs ...