Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic ...

Metabolic-dysfunction-associated steatotic liver disease (MASLD) arises from excessive intrahepatic triglyceride accumulation ...

Further analysis showed that Asah1 deficiency increased harmful lipids accumulation, disrupted lipid metabolism ... by regulating hepatic lipid homeostasis and cellular maintenance processes.

The fate of some of the IDL particles requires them to be reabsorbed by the liver (again by the LDL receptor); however, other IDL particles are hydrolyzed in the liver by hepatic-triglyceride ...

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

Researchers have now determined that hepatic stellate cells control liver metabolism as well as liver regeneration and size. The results of the study could contribute to new therapeutic approaches ...

Discover preclinical studies that indicate that empagliflozin reduces liver fat, improves liver function markers, and ...