Metabolic-dysfunction-associated steatotic liver disease (MASLD) arises from excessive intrahepatic triglyceride accumulation ...

The fate of some of the IDL particles requires them to be reabsorbed by the liver (again by the LDL receptor); however, other IDL particles are hydrolyzed in the liver by hepatic-triglyceride ...

Solute carrier (SLC) family transporters are crucial transmembrane proteins responsible for transporting various molecules, including amino acids, electrolytes, fatty acids, and nucleotides. To date, ...

Central to these discussions is the role of the pituitary-targeted gland axes (PTGA) in regulating hepatic lipid metabolism.

Hepatic ischemia-reperfusion injury (IRI) is a common and unavoidable complication associated with liver transplants that may ...

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic ...

Hitting a plateau after a steady run of weight loss has derailed many health and fitness plans. But what if you could flick a ...

The team knew from previous studies that humans born without this gene have problems with their lipid metabolism, a ...

Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...