Horseshoe crabs, the blue-blooded burrowers in the genus Xiphosura, first appeared in the fossil record about 450 million years ago. Around that same time, arachnids crawled into existence.

Horseshoe crabs are used by around a dozen fishermen around Long Island in traps for eels and whelk, or conch. Seen here: a baby horseshoe crab in 2015. Credit: David L. Pokress.

Each spring, guided by the full moon, hundreds of thousands of horseshoe crabs clamber onto beaches across the U.S. mid-Atlantic to lay their eggs.For hungry birds, it’s a cornucopia. For drug ...

Horseshoe crabs may be spared in the near future, however. On Friday, the U.S. Pharmacopeia, an organization that sets standards for the biomedical industry, issued guidance on using synthetic ...

Horseshoe Hotel and Casino is undergoing a multi-million-dollar hotel renovation. (Horseshoe) “We want to offer our guests a new experience, something they can be excited about, and we think that they ...