Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 nd in the open-access journal ...

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that ...

“Precision editing technologies like CRISPR/Cas9 are incredibly promising as therapies,” geneticist Daniel MacArthur of the Broad Institute of Harvard and MIT tells The Scientist in an email. “They’re ...

Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

Next-generation sequencing technologies have catapulted the field of genomics back into the spotlight thanks to fast, accurate, and historically low-cost sequencing methods. As of today, the cost of ...

A watercolor artist’s interpretation of the relationship between the human genome and gut mycobiome. Created by Amy Bean, watercolor journalist and mom of first author Emily Van Syoc. Clinicians’ ...

“The important part of the work is the large number of [exomes],” Stephen Scherer, who studies variation in the human genome at the Hospital for Sick Children and the University of Toronto, Canada, ...

Why do no two human faces look quite the same? Although we all follow the same biological blueprint, our features—the curve ...