Aim: The present study aimed to investigate the human genetic diversity of the CYP450 superfamily in order to identify functional interethnic differences and analyze the role of CYP450 enzymes in ...

Using a combination of laboratory techniques and statistical analyses, the team studied the naturally occurring genetic variation between humans in blood cells from 34 people, focusing on DNA ...

From understanding hereditary diseases to predicting drug responses, sequencing helps researchers uncover the subtle language ...

Structural variants in the human genome include cytogenetically detectable and submicroscopic deletions, duplications, large-scale copy-number variants, inversions and translocations. The ability ...

Kidney disease, leading to kidney failure, afflicts disproportionately more black people than white people. Thus, there is a ...

One in 10 Americans live with a rare disease, which often lacks effective treatments. Such is the case for PIGA-CDG, an ultra ...

In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define ...

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle.

This revealed that large-scale deletions of the genetic code, especially in non-coding regions, did not seem to impact the gene expression of the rest of the cell. The researchers suggest that human ...