Scientists at Ghent University have created a mouse model that incorporates human versions of the receptors that recognize the fragment crystallizable (Fc) region of immunoglobulin G (IgG), one of the ...

The MPI team has chosen the humanized mouse as a model organism for its investigations. In these animals, the existing mouse gene was exchanged for the human FKBP5 gene. The results that the ...

In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Flow cytometry enables researchers to label proteins of interest using fluorophore-conjugated antibodies and other fluorochromes. Much like immunohistochemistry, which produces two- or ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Taconic Biosciences, Inc., a global leader in genetically engineered rodent models (GEMs) and humanized immune system (HIS) mouse models, today announced the acquisition of TransCure bioServices SAS, ...

RENSSELAER, N.Y. & ARCHAMPS, France--(BUSINESS WIRE)--#acquisition--Taconic Biosciences, Inc., a global leader in genetically engineered rodent models (GEMs) and humanized immune system (HIS) mouse ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.