Familial hypercholesterolemia (FH) is a genetic disorder characterized by high levels of low-density lipoprotein cholesterol (LDL-C) in the blood, which significantly increases the risk of ...
Familial hypercholesterolemia results from gene ... and premature coronary artery disease. Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently ...
In a new study just published in the European Heart Journal, researchers from Herlev and Gentofte Hospital quantify for the first time how life expectancy and cardiovascular disease in people ...
Coronary heart disease (CHD) is a leading cause of morbidity and mortality globally. Hypercholesterolemia is one of the major risk factors for CHD. With the increase in aging populations and ...
The firm’s second candidate, VERVE-102, also targets patients with heterozygous familial hypercholesterolemia and premature coronary artery disease. Although it uses the same base-editing ...
A zero calcium score with high cholesterol may mean a person is at a lower risk of coronary heart disease. It means imaging does not show a buildup of calcified plaque in the heart’s blood vessels.