Scientists at the University of California, San Diego School of Medicine have described for the first time a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, ...

MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection. "I just can't make it tonight. You ...

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to ...

Science Progress (1933-), Vol. 104, No. 4 (2021), pp. 1-21 (21 pages) By using an animal model in which inflammatory cytokines are induced in lipopolysaccharide (LPS)-injected rat brain, we ...

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to ...

The Company recently announced that it would advance development of TZLS-501, a dual-action IL-6R monoclonal antibody targeting both membrane-bound and soluble forms of IL-6R. This decision was based ...

Tiziana Life Sciences has pointed to increased Big Pharma interest in the IL-6 pathway as justification for its ...

The IL-6 receptor antagonist market presents significant opportunities in underexplored areas like thyroid eye disease and atherosclerotic cardiovascular disease (ASCVD). Recent acquisitions and ...