Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for ...

Explores how inhalational anesthetics trigger general anesthesia through interaction with calcium channel RyR1.

Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their anesthetic ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), which contributes to the induction of general ...

Inhalational anesthetics are also associated with a higher incidence of nausea, vomiting, and emergence agitation than intravenous anesthetics. 5 Clinicians must remain alert and be prepared to ...

Volatile anesthetics produce safe, reversible unconsciousness, amnesia and analgesia via hyperpolarization of mammalian neurons. In molluscan pacemaker neurons, they activate an inhibitory ...

Cannabis users aged 65 years or older undergoing general anesthesia for surgery required higher doses of inhalational anesthetics than nonusers. However, the clinical relevance of this difference ...

The research group first confirmed that isoflurane and other inhalational anesthetics activate RyR1 and stimulate calcium release from the endoplasmic reticulum *2. The amino acid residues in RyR1 ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), ...