Background Many observational studies highlight clonal haematopoiesis (CH) as a novel determinant of cardiovascular disease ...

In a situation like yours, I’d recommend a prenup. Full disclosure: Years ago, I used to be completely against them. I’d tell folks not to get married if they loved money and material stuff more than ...

Co-parenting can be complicated long after a breakup. If your ex wanted you to give them things that used to be your children’s, would you agree to it or refruse? This man is divorced but co-parents ...

Background: Low-dose methotrexate (MTX) is a standard treatment for ectopic pregnancy. While generally safe, it can rarely cause life-threatening hematologic toxicity. The mechanisms underlying these ...

Background Autosomal dominant (AD) inheritance often arises through haploinsufficiency, dominant-negative or gain of function (GoF) effects, while autosomal recessive (AR) inheritance generally ...

A condo owned by Tony Award-winning producer Luigi Caiola is on the market for the first time with a listing price of $19.39 million, which includes the custom furnishings and most of the art. Caiola, ...

Family dynamics can get tricky, and this story about two sisters, a hefty inheritance, and a destination wedding is a perfect example. "My sister (32, female), on the other hand, lives out of state.

The federal estate tax exemption increased again for 2025. Although the higher, IRS-inflation-adjusted number, announced last fall, may not have come as a surprise to most. However, 2025 is a pivotal ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The paternal preconception environment has ...

Introduction: Netherton syndrome (NS) is a rare autosomal recessive disorder caused by mutations in the SPINK5 gene, which encodes the serine protease inhibitor LEKTI. It is characterized by ...