Miao et al. show that loss of neuronal Vps13d in mice leads to mitochondrial dysfunction, GSDME-mediated mitochondrial DNA release, cGAS–STING inflammatory signaling, and activation of microglia, ...

DAKOTA CITY, Neb. — When Renate Rosentrader got her letter in the mail in June she thought it was just another case of some company somewhere trying to sell her something she didn’t need.