T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Recent developments in the field include an evolving treatment landscape and the development of evidence-based guidelines.

Investigative therapies to treat moderate to severe plaque psoriasis in clinical trials include several orally administered ...

Abl tyrosine kinase activity was determined using a synthetic peptide (EAIYAAPFAKKK) as substrate. The activities of Lyn and Csk tyrosine kinases were assayed using a Src substrate peptide ...

Could interleukin-1 antagonists be the answer to managing acute gout? Guidelines for the management of this disorder, issued by the European League Against Rheumatism (EULAR) and the British ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

Study shows how 60 minutes of moderate exercise affects hunger hormones, potentially making weight loss easier for those struggling with appetite control.

Serum soluble interleukin-2 receptor (sIL-2R) levels have been a great diagnostic tool for non-Hodgkin lymphoma (NHL) and ...