Murine Ba/F3 cells were transfected with cDNA for the α-chain of the murine interleukin-5 (IL-5) receptor and cloned lines of these cells were able to proliferate in response to as little as 2.5 ...

Interleukin-5 (IL-5) has been suggested to be involved in the development of airway hyper-responsiveness (AHR). Both clinical and experimental investigations have shown strong correlation between ...

The field of cytokine biology has seen significant advancements, particularly concerning Interleukin-5 (IL-5) and its role in eosinophil-related disorders.

Levels of interleukin-5, eotaxin, and eosinophil cationic protein also declined dramatically after antibody administration . Table 1. ...

Anti–Interleukin-5 Monoclonal Antibody to Treat Severe Eosinophilic Asthma Author : Parameswaran Nair , M.D., Ph.D. Author Info & Affiliations Published September 25, 2014 ...

GSK plc’s interleukin-5 (IL-5) portfolio got boost as depemokimab, an ultra-long-acting biologic targeting IL-5, hit its endpoints in two phase III trials in severe asthma, setting up potential ...

Background: Combined immunochemotherapy with interleukin 2, interferon alpha and 5-fluorouracil in patients with metastatic renal cell carcinoma has shown objective response rates up to 30% and more.

Treatment: IL-2 10MIU/m 2, SC x 3/week, weeks 1–4; IFN- α 6MIU/m 2, SC once a week, weeks 1–4 and 10MIU/m 2 x 3/week, weeks 5–7; 5-FU 600mg/m 2 and VBL 6mg/m 2, iv bolus, weeks 5 and 8. Each treatment ...

Major players in the interleukin inhibitors market are Sanofi, GlaxoSmithKline, Novartis, Johnson & Johnson, Roche, Eli Lilly, AstraZeneca, Teva Pharmaceutical and Regeneron Pharmaceuticals.New ...

Interleukin-6 (IL-6) is a pleiotropic cytokine secreted by T cells and macrophages to activate immune responses during infection or after trauma. IL-6 plays an important role in a number of bodily ...