Anti-IL5 therapy significantly reduces moderate and severe exacerbations in asthma and COPD, preventing major ...

Monoclonal antibodies targeting IgE, interleukin-4 and -13, and interleukin-5 are effective in treating severe type 2 asthma, but new targets are needed. Itepekimab is a new monoclonal antibody ...

白细胞介素（IL-4，Interleukin-4）是免疫系统中的一种重要调节因子，它参与感染、过敏、自身免疫和癌症等多种免疫反应。而重组IL-4（重组白介素4，AbMole，M10465）为免疫细胞的培养和分化诱导，以及细胞和动物实验提供了重要工具。AbMole为全球科研客户提供高纯度、高生物活性的抑制剂、细胞因子、人源单抗、天然产物、荧 ...

Randomized trial data support the use of either TNF or IL-17 inhibitors to treat axial spondyloarthritis, based on patient ...

Dupilumab (interleukin-4Rα; antibody binds to interleukin-4Rα, inhibiting interleukin-4 and interleukin-13 signaling in hematopoietic cells [e.g., B cells, CD4+ helper T cells, and eosinophils], ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2005 ASCO Annual Meeting. This abstract does not include a full text component.

A plasmid DNA vaccine encoding prostatic acid phosphatase (PAP) elicits antigen-specific T cells in patients with stage D0 prostate cancer No significant financial relationships to disclose. This is ...

An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding ...

Dupilumab significantly reduced exacerbations in adults with chronic obstructive pulmonary disease by approximately 30% compared with placebo, based on data from approximately 900 individuals. Chronic ...