The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...
emory.edu Background The extent to which numerous strains of genetically engineered mice, including mice lacking Toll-like receptor 5 (T5KO), display colitis is environment dependent ... Consequently, ...
Five patients with refractory SLE were treated daily with subcutaneous injections of 1.5 million IU of human IL-2 (aldesleukin) for five consecutive days, and PBMC were analysed by flow cytometry.
To demonstrate the efficacy of targeting interleukin 6 receptor in patients with Sjögren’s syndrome-related systemic ... Inclusion criteria were primary Sjögren’s syndrome according to American ...
Amongst the drug classes used within the dermatology space, interleukin (IL) inhibitors were highlighted as a major growth driver. Additional insights into pipeline development indicate an exciting ...