Murine Ba/F3 cells were transfected with cDNA for the α-chain of the murine interleukin-5 (IL-5) receptor and cloned lines of these cells were able to proliferate in response to as little as 2.5 ...

Interleukin-5 (IL-5) increases the secretion of natural T15/EO6 IgM antibodies that inhibit the uptake of oxidized low-density lipoprotein (LDL) by macrophages. This study aimed to determine ...

Levels of interleukin-5, eotaxin, and eosinophil cationic protein also declined dramatically after antibody administration . Table 1. ...

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The field of cytokine biology has seen significant advancements, particularly concerning Interleukin-5 (IL-5) and its role in eosinophil-related disorders.

Interleukin-31 plays a role in the pathogenesis of atopic dermatitis and, more specifically, in the occurrence of pruritus. 16–21 Nemolizumab (CIM331), 22 a humanized monoclonal antibody against ...

Background: Combined immunochemotherapy with interleukin 2, interferon alpha and 5-fluorouracil in patients with metastatic renal cell carcinoma has shown objective response rates up to 30% and more.

GSK plc’s interleukin-5 (IL-5) portfolio got boost as depemokimab, an ultra-long-acting biologic targeting IL-5, hit its endpoints in two phase III trials in severe asthma, setting up potential ...

Treatment: IL-2 10MIU/m 2, SC x 3/week, weeks 1–4; IFN- α 6MIU/m 2, SC once a week, weeks 1–4 and 10MIU/m 2 x 3/week, weeks 5–7; 5-FU 600mg/m 2 and VBL 6mg/m 2, iv bolus, weeks 5 and 8. Each treatment ...

Major players in the interleukin inhibitors market are Sanofi, GlaxoSmithKline, Novartis, Johnson & Johnson, Roche, Eli Lilly, AstraZeneca, Teva Pharmaceutical and Regeneron Pharmaceuticals.New ...

This chemical interacts with interleukin-6 receptor alpha, to induce transcription of inflammatory gene products. IL-6 is implicated in a host of chronic disease conditions associated with ...