Fe is essential for plant growth and human nutrition, yet its accumulation must be tightly regulated to avoid toxicity. We uncover a dual role of abscisic acid (ABA) in balancing seed Fe homeostasis: ...

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies ...

Iron dysregulation contributes to MS progression through oxidative stress, ferroptosis, and immune activation, affecting neuronal and immune cell function. Both iron overload and deficiency exacerbate ...

Brain iron measured by quantitative susceptibility mapping MRI predicted cognitive decline in healthy older adults. Higher magnetic susceptibility in two brain regions was tied to a higher risk of ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

Taylor Leamey wrote about all things wellness for CNET, specializing in mental health, sleep and nutrition coverage. She has invested hundreds of hours into studying and researching sleep and holds a ...

Departamento of Chemistry, Federal University of Espírito Santo (UFES), Av. Fernando Ferrari, 514, Vitória, Espírito Santo 29075-910, Brazil Department of Physiological Sciences, Federal University of ...

Schematic hypothesis. Ischemic stroke causes iron accumulation, disrupting the redox balance, which in turn leads to two outcomes. One of the outcomes is the increased cell susceptibility to ...