Hepatocytes, as the most abundant cell type in liver, are a potent source of fibrogenic lipid peroxides in inflammatory liver diseases. Platelets are a potent source of growth factors, and are ...

Investigation of the molecular mechanisms underpinning complex liver diseases and their pathology is an emerging goal of stem cell scope. Human induced pluripotent stem cells (hiPSCs) derived from ...

Here, we report that TRAIL is constitutively expressed on murine natural killer (NK) cells in the liver and plays a substantial role in suppressing tumor metastasis. Freshly isolated NK cells ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. Macrophages are specialized immune cells located in every ...

As a metabolic center, the liver prevents inappropriate immune responses to abundant dietary antigens within the liver that could result in liver injury. This self-preservation mechanism can however ...

People with cirrhosis are at an increased risk of liver cancer. Treatment may include surgery, a liver transplant, ablation therapy (a needle or probe is used to kill cancer cells), embolization ...

Lung cancer liver metastases are tumors that form in the liver from cancer cells that have broken away from the primary cancer and spread through the blood or lymphatic system. The liver is a common ...

Unexpectedly, the frequency of Th17 cells was significantly decreased in the joints compared with PBMC of the same patients with RA, whereas Th1 cells were more abundant in the joints than in PBMC.

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

The rest of the alcohol can damage and destroy liver cells. The liver is very good at regenerating itself. However, in people who regularly drink too much alcohol, the damaged liver cannot ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...