直接MALDI-TOF MS快速鉴定病原体在血液等无菌体液中的应用研究，发现其可在30-60分钟内完成病原体鉴定，但存在革兰氏阴性菌识别率高于阳性菌及真菌的现象，主要受样本中微生物浓度、细胞壁结构及蛋白质提取效率影响，同时面临低灵敏度样本、基质干扰、多 ...

艰难梭菌（Clostridioides difficile）感染（CDI）是最常见的医疗相关感染之一，导致显著的发病率和死亡率。CDI的诊断需要临床评估和实验室检测。本研究旨在评估MALDI-TOF质谱技术在识别产毒艰难梭菌菌株方面的有效性。 方法 从2019年5月到2024年3月，所有通过PCR检测 ...

MALDI-TOF MS yields absolute molecular weights not relative ones. MALDI-TOF MS is a fast and versatile method to address challenges in the synthesis or quality control of polymers. Structural features ...

Bruker Corporation BRKR recently announced the launch of the neofleX Imaging Profiler for mass spectrometry-based tissue imaging at the 72nd ASMS meeting. The novel, high-performance MALDI-TOF/TOF ...

neofleX is a versatile, high-performance, and easy-to-use multiomics MSI system for biopharma, translational and clinical researchers neofleX Imaging Profiler MALDI-TOF/TOF with proprietary smartbeam ...

The inimitable adaptability of MALDI-TOF/TOF systems enables tissue imaging of intact proteins, as well as of tryptic peptides brought about by on-tissue digestion. Although intact protein imaging can ...

It's been 20 years since Hillenkamp and Karas developed MALDI. In that time, the soft ionization method, coupled with time-of-flight (TOF) mass spectrometry, has distinguished itself as the enabling ...

Matrix-assisted laser desorption ionization – time of flight (MALDI-ToF) mass spectrometry is to be added to Public Health England’s (PHE’s) standard microbiological test methods. MALDI-ToF mass ...