Another cell therapy biotech has run out of steam, this time before ever reaching the clinic. California CAR-T company Appia Bio has closed up shop, founding CEO JeenJoo “JJ” Kang, Ph.D., wrote in an ...

Social Security is 90 years old, and a new report from American Association of Retired Persons shows a sharp decline in confidence in the program’s future – especially among younger adults. The report ...

While the 10-fold increase in dose over injectable Wegovy has raised questions about the launch, Novo Nordisk has assured investors it has the manufacturing capacity to roll out oral semaglutide ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Nuclear factor erythroid 2-related factor 2 ...

Risk Stratification for Sentinel Lymph Node Positivity in Older Women With Early-Stage Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2 Neu–Negative Invasive Breast Cancer Data for ...

A proposal to bring all local public bus service in-house would sharply increase costs compared with continuing to outsource, but the change would likely make buses more reliable and efficient, a new ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Phospholipase C gamma 1 (PLCG1) has been ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. In the postpandemic era, the development of nucleic acid-based ...

Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. AKT is the main protein kinase of the PI3K-AKT pathway, interacting with over one ...

ProKidney’s cell therapy for kidney disease failed to demonstrate a clinically significant preservation of kidney function in one part of a phase 2 study, but the biotech has pointed to the trial’s ...

The success of 3D bioprinting in tissue engineering relies on i) precise bioink deposition for creating intricate tissue architectures and ii) good cell viability after printing. However, printed ...