Division of Physiological Chemistry and Metabolism, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan Laboratory of Metabolomics, RIKEN Center for Integrative ...

They found that three types of immune cells needed to be present for the tumor to respond to treatment: fighter cells called T and NK cells, and cells called macrophages, which present flags on ...

Macrophages also contribute to insulin resistance in type 2 diabetes by releasing inflammatory molecules that impair glucose metabolism, complicating the management of diabetes in obese patients.

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

The impact of the complement system on iron metabolism and its role in gastric cancer progression is an area warranting further investigation. Our research demonstrates that the C5a-C5aR pathway ...

Citation: Macrophages, not T cells, may hold key to predicting which melanoma patients are more likely to respond to immunotherapy (2025, January 8) retrieved 2 February 2025 from https ...