Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

One of the mechanisms that helps cells to deal with replication stress and restart DNA replication is fork reversal, a pathway that can facilitate replication stress relief. This mechanism involves ...

Conjugation is a form of horizontal gene transfer that allows the exchange of genetic material between two organisms or cells ...

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between ...

“While mtDNA is much smaller than nuclear DNA, it plays a crucial role ... which further intrigued me to explore the mechanism of mtDNA replication and maintenance in real depth,” says Dr.

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

During DNA replication, the double helix unwinds ... Cells have evolved various DNA repair mechanisms to correct such mutations. One such mechanism is base excision repair (BER), where the mutated ...