An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding ...

Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

They observe how the mobile DNA LINE-1 copies its sequence in human cells, revealing the precise mechanism of the ORF2p gene.

Breakthrough cryo-EM structures expose multiple drug targets in an essential HSV-1 replication protein.An international ...

Long Interspersed Nuclear Element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

These burrowing animals have a biological mechanism that does the opposite of what it does in humans: it repairs DNA instead ...

Reviewers viewed the targeting of TFAM as innovative and the study's conclusions as potentially important (especially the effects on inflammation). However, the lack of evidence for a direct effect of ...

Volume 646 Issue 8086, 23 October 2025www.nature.com/nature/volumes/646/issues/8086Editorial 社论What makes PhD students happy? Good supervision博士生何以快乐？良师指导是关键与博士生建立积极指导关系的导师，也会从自己的研究中获益。哪些因素对博士满意度的影响最大 ...

Results from pritelivir Phase 2 study demonstrate a favorable safety profile and a numerically higher lesion healing rate vs. foscarnetPritelivir Phase 2 results supported FDA Breakthrough Therapy ...

Objectives Patients with primary Sjögren’s disease (SjD) have an increased risk of B cell lymphoma. The aim of this study was ...

This study addresses an important question in liver biology: how zonal hepatocytes balance survival and proliferation following injury; using spatial transcriptomics, mechanistic perturbations, and ...