Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

Additionally, mechanisms underlying DNA sequence alteration have been found to act as predictors of tumorigenesis, as well as directly influence therapy response. Thus, gaining a deeper understanding ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells that can remain unrepaired for years. While most types of DNA damage are ...

Find all the information you need to apply to the Baylor College of Medicine Graduate School of Biomedical Sciences.

Combining long-read DNA sequencing with a predictive artificial intelligence model has provided new insights into DNA replication.

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ... copied during cell division -- known as DNA replication -- and this introduces permanent mutations ...

Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...