Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958 ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that ... that loads a "clamp" onto DNA to keep parts of the replication machinery from falling ...

Conjugation is a form of horizontal gene transfer that allows the exchange of genetic material between two organisms or cells ...

Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogenous and ...

“While mtDNA is much smaller than nuclear DNA, it plays a crucial role ... which further intrigued me to explore the mechanism of mtDNA replication and maintenance in real depth,” says Dr ...

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

Researchers have uncovered mechanisms by which mobile genetic elements integrate into the chromosomes of bacteria with linear genomes.