Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue.

Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering ...

The Semaglutide peptide has emerged as a compelling subject in biochemical and physiological research due to its potential ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

All metabolic pathways have to be regulated and controlled to stop the build-up of an end product that isn’t needed. The cell can control a metabolic pathway by the presence or absence of a ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

To better conduct the analysis of nucleoside analogues, hydrophilic interaction liquid chromatography–tandem mass ...

This intricate connection between the gut microbiome and joint health underscores the potential of targeting gut-derived pathways for OA treatment. "The gut-joint axis is a relatively new concept ...

Chronic spontaneous urticaria (CSU) has a causal association to gut microbiota, with the metabolic pathway being a potential mediator, providing new insights for further mechanistic and clinical ...

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows. Published ...