BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

Besides frustrating changes to their hormones, muscle mass and skin, quadragenarians like Kardashian and Johnson also have to worry about a drop in their NAD⁺ levels.

Version of Record: This is the final version of the article. The study conducted by the Schuldiner's group advances the understanding of mitochondrial biology through the utilization of their ...

SUMMIT, N.J., Dec. 3, 2025 /PRNewswire/ -- Vascarta Inc., is pleased to share results from a new study led by researchers at the U.S. Food and Drug Administration's Center for Biologics Evaluation and ...

Millions of people worldwide live with mitochondrial diseases. These are inherited conditions that make it hard for the body’s cells to produce energy. For a long time, patients had few options ...

This study reports a dynamic association/dissociation between malate dehydrogenase (MDH1) and citrate synthase (CIT1) in Saccharomyces cerevisiae under different ...

Scientists have developed oral nanorobots that target damaged heart tissue, deliver energy, and repair mitochondrial function, offering a novel approach to treating ischemic heart disease. (Nanowerk ...

Abdominal aortic aneurysm (AAA) is a complex vascular pathology without pharmaceutical interventions. This study aimed to evaluate whether restoring vascular smooth muscle cell (VSMC) mitochondrial ...

ClpXP is a mitochondrial matrix protease that degrades damaged or misfolded proteins and helps maintain mitochondrial health and cellular function. Much like how ubiquitin tags proteins for ...