This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed ...

But it's important to show the mechanisms of these helicases, because they're essential for DNA replication, and also possible drug targets." Yang Gao, Assistant Professor, Biosciences, Rice ...

He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...

The fact that TAg was expressed after DNA replication suggested it was expressed too late to be responsible for driving cells into replicating their DNA. Sunnie Thompson, Ph.D. TAg expression and ...

Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target Date: March 10, 2025 Source: Memorial Sloan Kettering Cancer Center ...

Synthesis of 32 P-Labeled DNA Chain and Its Subsequent Enzymatic Degradation by Micrococcal DNase and Calf-Spleen Phosphodiesterase to 3′ Deoxyribonucleotides (Modified from Kornberg 37).

Telomir Pharmaceuticals Announces Telomir-1 Resets the Body’s Epigenetic Clock, Reverses DNA Methylation, and Restores Youthful Gene Regulation in an Ultra-Rare Accelerated Aging Animal Model of ...

"Our study model, the mouse liver, is an ideal organ for studying the mechanisms of DNA replication in vivo. In adult mammals, hepatocytes rarely proliferate unless they have been partially ablated.

Mrc1 is part of a group of proteins called the fork protection complex (FPC), which is part of the replisome, a molecular machine that coordinates the replication of DNA, a process that includes ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues ...

Their findings, which were published March 7 in Science, one of world’s leading scientific journals, not only reveal new details about how secondary DNA structures like G4s can impede DNA replication, ...