Protein serine/threonine kinases (STKs) regulate critical signaling pathways involved in cell growth, proliferation, metabolism, and apoptosis. Aberrant kinase activity is implicated in diverse human ...

The rapid advancement of artificial intelligence (AI) is transforming the field of structural biology. In May 2024, DeepMind and Isomorphic Labs launched AlphaFold 3 (AF3), a revolutionary AI system ...

AlphaFold2 and other machine learning-based methods can accurately predict the structures of most proteins. However, nearly two-thirds of human proteins contain segments that are highly flexible and ...

Chemistry Department, Faculty of Education and Applied Sciences─Arhab, Sana’a University, Sana’a 1247, Yemen Chemistry Department, Faculty of Science, Mansoura University, Mansoura 35511, Egypt ...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and amyloid-β (Aβ) accumulation. Increasing evidence suggests that dietary bioactive compounds ...