Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are major complications that occur in severely ill patients who require intensive care treatment. CIP and CIM affect the ...

Critical illness myopathy (CIM) detrimentally affects muscle function in ICU patients, with a dramatic loss of muscle mass and function where the loss in specific force exceeds the loss in muscle mass ...

Additional features included central nervous system (CNS) involvement (lissencephaly (n=3), polymicrogyria (n=5)), neuropathy (n=2) and congenital myopathy (n=5). Recruitment into this project was via ...

Left ventricular (LV) mass loss is prevalent in doxorubicin (DOX)-induced cardiotoxicity and is responsible for the progressive decline of cardiac function. Comparing with the well-studied role of ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...

The genetics of the collagen VI related muscular dystrophies are complex. Independent description of the two distinct clinical phenotypes, Bethlem myopathy and Ullrich congenital muscular dystrophy, ...

Correspondence to: Dr Perry Elliott The Heart Hospital, 16–18 Westmoreland Street, London, W1G 8PH, UK; pelliott{at}doctors.org.uk Lysosomal storage disorders (LSD) comprise a group of more than 40 ...

Clinical Physiology provides diagnostic methods to detect and evaluate dysfunction of various organs and systems in the body such as the heart, peripheral vessels, lungs, kidneys, gastrointestinal ...

Hand held dynamometry is sensitive for the detection of weakness and for the clinical evaluation of treatment effects. Weakness in hypothyroidism is more difficult to treat, suggesting myopathy.