The drug promotes lipophagy and hepatic fatty acid beta-oxidation to reduce liver fat, inflammation, and liver fibrosis.

There is a strong inverse relationship between estimated glucose disposal rate (eGDR) and liver fibrosis severity in adults with obesity and nonalcoholic fatty liver disease (NAFLD), according to ...

Insights into the interactions between HO-1 and SIRT1 in NAFLD-associated liver fibrosis could facilitate the development of new biomarkers and treatment strategies for liver dysfunction.

Liver biopsies were conducted at baseline and 72 weeks. Three pairs of pathologists reviewed liver histological slides to determine fibrosis stage and NAFLD activity score.

Nonalcoholic fatty liver disease (NAFLD) is a common comorbidity in hypertension. However, the impact of NAFLD and related fibrosis on hypertension and its control of cardiovascular disease (CVD) and ...

MAFLD, NAFLD, and the Risk of Peripheral Artery Disease —A study from two large cohorts assessed patients who fit the criteria for metabolic dysfunction–associated fatty liver disease or non ...

CLINICALLY significant liver fibrosis is a key predictor of adverse outcomes in patients with steatotic liver diseases, such as non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver ...

Tools such as the NAFLD Fibrosis Score (NFS), Fibrosis-4 (FIB-4), and NAFLD Fibrosis Protein Panel (NFPP) provide valuable information regarding the extent of liver damage and help guide clinical ...

Key methods include blood-based biomarkers such as the Fibrosis-4 (FIB-4) score, NAFLD Fibrosis Score (NFS), and Enhanced Liver Fibrosis (ELF) test, as well as imaging modalities like ...

Noninvasive liver fibrosis scoring systems may help identify who is at risk of developing heart failure.