“S. Typhimurium infection of mice led to a high level of lipocalin 2 expression in the epithelial cells lining the villi and crypts of the ileal mucosa.” ...
The research was published in the journal Nature Microbiology. Zhiyu Zang ... This natural product effectively sequestered iron from Bacillus subtilis, hindering its ability to defend itself ...
Pereira et al, The Parkinson's disease drug entacapone disrupts gut microbiome homoeostasis via iron sequestration, Nature Microbiology (2024). DOI: 10.1038/s41564-024-01853-0 ...
has identified the full sequence of protein–protein interactions during this iron "theft." The findings, published in Nature Communications, open possibilities for developing pharmaceuticals to ...