The high-temperature requirement A (HtrA) family of serine proteases has been shown to play an important role in the environmental and cellular stress damage control system in Escherichia coli.

NEW research from South Africa highlights the clinical challenges posed by bedaquiline-resistant rifampicin-resistant tuberculosis (RR-TB), revealing significantly delayed microbiological responses ...

Bacteria can precisely adjust their membrane lipid compositions to control the biophysical properties of their membranes, which allows them to thrive in various physical environments. Here ...

The emergence of multidrug- and extensively drug-resistant strains of Mycobacterium tuberculosis highlights the need to discover new antitubercular agents. Here we describe the synthesis and ...

Both the WHO and Canadian Tuberculosis Standards (CTS; 2022) recommend systematic testing and treatment of patients initiating immunosuppressive drugs associated with high risk for TB reactivation.