A report has shown that genetic deletion, or mutation, of TET2 and TET3 in mouse B cells damps down the generation of functional IgG antibodies, decreasing the effectiveness of immune responses. A ...
Some of the most important proteins were follistatin and cathepsin D. These proteins were found at higher levels in people ...
The scientists' new 'binder-tag' technique allows researchers to pinpoint and track proteins that are in a desired shape or 'conformation,' and to do so in real time inside living cells. The ...
Researchers from the University of Texas Southwestern Medical Center have discovered how nerve cells recruit corrupted proteins that then corrupt other normal proteins within the cell, leading to ...
The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...
All forms of amyloidosis are caused by the abnormal folding of proteins in our body’s cells. In the case of wild-type ATTR amyloidosis, normal proteins accumulate but are not cleared from organs, ...
Prion diseases occur when normal prion protein, found on the surface of many cells, becomes abnormal and clumps in the brain, causing brain damage. Prion diseases or transmissible spongiform ...
New research from the University of Cincinnati bolsters a hypothesis that Alzheimer’s disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been ...
Others studies have suggested that alpha-synuclein fibrils can seed new clumps of diseases proteins in healthy cells. In 2008, two teams showed that normal fetal neurons develop Lewy bodies if they’re ...
LA JOLLA, CA--A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear ...
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