Researchers have pinpointed what causes normal proteins to convert to a diseased form, causing conditions like CJD and Kuru. For the first time, researchers have pinpointed what causes normal proteins ...

A report has shown that genetic deletion, or mutation, of TET2 and TET3 in mouse B cells damps down the generation of functional IgG antibodies, decreasing the effectiveness of immune responses. A ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

Prion diseases occur when normal prion protein, found on the surface of many cells, becomes abnormal and clumps in the brain, causing brain damage. Prion diseases or transmissible spongiform ...

Researchers from the University of Texas Southwestern Medical Center have discovered how nerve cells recruit corrupted proteins that then corrupt other normal proteins within the cell, leading to ...

A serum immunofixation test measures specific proteins in your blood. It helps to identify certain illnesses that are otherwise hard to detect, such as multiple myeloma, a blood cancer. The test is ...

All forms of amyloidosis are caused by the abnormal folding of proteins in our body’s cells. In the case of wild-type ATTR amyloidosis, normal proteins accumulate but are not cleared from organs, ...

Others studies have suggested that alpha-synuclein fibrils can seed new clumps of diseases proteins in healthy cells. In 2008, two teams showed that normal fetal neurons develop Lewy bodies if they’re ...

New research from the University of Cincinnati bolsters a hypothesis that Alzheimer’s disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been ...

LA JOLLA, CA--A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear ...