Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 24 (June 12, 2012), pp. 9420-9425 (6 pages) Protein domains are conspicuous structural units in globular ...

From muscle growth to cellular repair, proteins fuel everything in the body. However, not all proteins are created equal. The ...

Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...

Protein-degrader structure and function have been captured in unprecedented detail. Protein degraders are recognized as an exciting avenue for drug discovery and development, providing targeted ...