"Who will watch the watchers?" asked Roman poet Juvenal way back in the first century C.E. Nature has been addressing that ...

The prediction of protein structure with the use of artificial intelligence and machine learning (AI–ML) is poised to transform how and when three-dimensional (3D) biostructure information is ...

It is now relatively trivial to determine the order of amino acids in a protein. Figuring out how that order translates to a complicated three-dimensional structure that performs a specific ...

How a protein works and what it does is determined by its 3D shape — ‘structure is function’ is an axiom of molecular biology. Proteins tend to adopt their shape without help, guided only by ...

So far the trove consists of 350,000 newly predicted protein structures. DeepMind says it will predict and release the structures for more than 100 million more in the next few months—more or ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

In a new move, researchers have shown that protein design software can incorporate motion into its outputs. The resulting protein gives a wave with one arm as it binds and releases a calcium ion ...

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms ...

An AI called AlphaFold predicted structures for nearly every protein known to science. Those predictions aren’t without limits, some researchers say.

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

The structure of protein sets the foundation for its interaction with other molecules in the body and, therefore, determines its function. This article will cover the structural principles of ...