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生物通
25 天
肝脏特异性长非编码 RNA FAM99B:抑制核糖体生成与肝癌进展的全新 ...
它是重要的核仁蛋白,参与核糖体 RNA(ribosomal RNA,rRNA)加工,在核糖体生物发生的多个步骤中发挥作用。此前研究表明,在多种细胞类型中,DDX21 缺失会导致 18S 和 28S rRNA 水平显著降低 。它还与多种人类癌症的发展有关,如乳腺癌、胃癌、黑色素瘤、结直肠癌 ...
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