The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form ...

This work presents a redox-responsive strategy for precise RNA control via post-synthetic 2′-OH acylation. These introduced disulfide-containing acyl groups can be selectively cleaved upon exposure to ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

Biologists have discovered that disruptions in transfer RNA function can lead to the development of cleft lip and cleft palate. Cleft lip and cleft palate are among the most common birth defects, ...

According to research from a team at the University of Utah Health and the University of Nevada, Reno School of Medicine, ...

National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...

A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle ...

An experimental RNA therapy from Avidity Biosciences has early clinical trial results showing it reduced by half the expression of a gene at the root of a rare, inherited form of muscular dystrophy ...