资讯
A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...
What am I looking at? This is a 3D rendering of an RNA polymerase II enzyme from baker’s yeast, created using actual molecular data to reconstruct its shape and active sites. What looks like a ...
实验发现,在野生型(WT)和 rna dependent rna polymerase 6(rdr6)突变体(该突变体转基因沉默减少)中,不同引导 RNA 的编辑效率有所差异。同时,热激处理和 rdr6 突变体能够提高编辑效率,编辑结果呈现出以缺失为主的嵌合 DNA 修复模式。
15 天
AZoLifeSciences on MSNStudy Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage SitesNew study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for ...
RNA polymerase IV and V Exclusively found in plants, RNA polymerase IV and V are transcription enzymes that evolved as specialized forms of RNA polymerase II 4. Both enzymes produce small interfering ...
研究表明,该特征对于 rna 聚合酶 ii(rna pol ii)分区、基因激活和癌细胞表型而言,既是必要的,也是充分的。 研究结果揭示,失调的凝聚体特异性是多种肿瘤融合物共有的分子机制,凸显了凝聚体组成的功能作用,以及疾病遗传学在探究凝聚体特异性与功能关系方面的强大作用。
12 天
News-Medical.Net on MSNInhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancersResearchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...
This application note highlights how a novel RNA polymerase provides a seamless solution that reduces dsRNA formation, minimizing the need for additional purification steps while maintaining superior ...
RNA-dependent RNA polymerase (RdRp) is a key enzyme for SARS-CoV-2 genomic replication and transcription and, thus, for viral replication.
In addition to its newly launched CleanScribe RNA Polymerase, TriLink offers mRNA capping analogs (including the award-winning CleanCap® M6), mRNA raw materials (nucleotides and other IVT enzymes ...
The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...
The world is absolutely teeming with viruses. | To find RNA viruses hiding in genomic “dark matter,” researchers took advantage of one thing they all have in common: the RNA polymerase enzyme.
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