RNA biology is a dynamic field crucial to deciphering gene expression and cellular function while revealing the intricacies of disease mechanisms. Recently, ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

St. Jude researchers advance CASTs, enhancing precision and activity for next-generation genome-editing therapies.

They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes blister-like skin rashes, and influenza viruses ...

v. 1. Synthesis and purification of RNA substrates / Benoit Chabot -- Characterization of RNA / Paula J. Grabowski -- Splicing of mRNA precursors in mammalian cells / Ian C. Eperon, Adrian R. Krainer ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

An mRNA cancer vaccine carries its own immune booster and lights up when it starts working, showing treatment success in mice ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked cellular process called minor splicing. This tiny but vital mechanism turns ...